More than 100 experts and those responding to emergencies concerning toxic exposures bring their collective knowledge, expertise, and experience to the development of IPCS Poisons Information Monographs (PIMs) and IPCS Treatment Guides.

These monographs are a unique collection, providing advice on the prevention and treatment of poisoning. Their development represents a major undertaking by IPCS INTOX. The following are the collections of documents contained in the IPCS INTOX Databank.

IPCS Poisons Information Monographs (PIMs)

PIMs provide evaluated information on substances (chemicals, pharmaceuticals, poisonous plants, and poisonous and venomous animals) commonly involved in cases of poisoning. A PIM is a practical document designed to facilitate the work of poisons information specialists, clinicians and analytical toxicologists.

PIMs summarize the physico-chemical and toxicological properties of the substance, clinical features of toxicity resulting from different routes of exposure to the substance, the patient management and the supporting laboratory investigations.

IPCS Treatment Guides

These guides are concise documents which harmonize indications for the clinical management of poisoning cases. They deal with the management of symptoms, clinical conditions or syndromes commonly observed in toxic exposures.

Treatment Guides are prepared by experienced clinical toxicologists and pharmacists, reviewed by working groups and then incorporated into the IPCS INTOX Databank when consensus on clinical recommendations has been reached.

IPCS/EC Evaluation of Antidote Series

Antidote Monographs provide definitive and authoritative guidance on the use of antidotes to treat poisoning. This series summarizes and assesses, on an antidote-by-antidote basis, their clinical use, mode of action and efficacy. This series is an undertaking of IPCS and the Commission of the European Union (EC).

IPCS International Chemical Safety Cards (ICSCs)

Summarized health and safety information on nearly 1,300 chemicals for individuals at the workplace.

IPCS Environmental Health Criteria monographs (EHCs)

Comprehensive data from scientific sources for the establishment of safety standards and regulations.

CCOHS CHEMINFO Database

Chemical profiles of a wide variety of potential workplace hazards, including a detailed evaluation of health, fire and reactivity hazards, along with first aid recommendations.

WHO/FAO Pesticide Data Sheets

Basic information for safe use of pesticides.

UK Poison Information Documents (UK PIDs)

Detailed chemical and pharmaceutical monographs produced for poison centres by the UK National Poisons Information Service Centres.

International Agency for Research on Cancer (IARC)

In 1969, the International Agency for Research on Cancer (IARC) initiated a programme on the evaluation of the carcinogenic risk of chemicals to humans involving the production of critically evaluated monographs on individual chemicals. In 1980 and 1986, the programme was expanded to include evaluations of carcinogenic risks associated with exposures to complex mixtures and other agents. The objective of the programme is to elaborate and publish in the form of monographs critical reviews of data on carcinogenicity for agents to which humans are known to be exposed and on specific exposure situations; to evaluate these data in terms of human risk with the help of international working groups of experts in chemical carcinogenesis and related fields; and to indicate where additional research efforts are needed.

Candidate Substances Database

The Candidate Substances Database is a convenient tool for identifying over 120,000 chemical substances. This database allows users to conveniently and quickly locate information on chemical names and specific CAS Registry Numbers.

Each record contains identification information on a unique chemical substance, including chemical names and synonyms, the CAS registry number, and any other unique identifying numbers. Data is derived from authoritative CCOHS databases such as CHEMINFO, the RTECS(R) database from NIOSH, and the DSL/NDSL database from Environment Canada. Records are in English.

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