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ISOFLURANE ICSC: 1435
Date of Peer Review: March 2002

Ether, 1-chloro-2,2,2-trifluoroethyl difluoromethyl
2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
CAS # 26675-46-7 C3H2ClF5O
RTECS # KN6799000 Molecular mass: 184.5
UN #
EC #
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

In case of fire in the surroundings: use appropriate extinguishing media.
EXPLOSION


EXPOSURE


Inhalation Cough. Sore throat. Dizziness. Drowsiness. Headache. Unconsciousness. See Notes.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin Redness. Dry skin.
Protective gloves.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain.
Safety spectacles or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion (See Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Collect leaking and spilled liquid in sealable containers as far as possible. Ventilation. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Personal protection: self-contained breathing apparatus.
EU Classification
UN Classification

EMERGENCY RESPONSE SAFE STORAGE

Ventilation along the floor.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2004

SEE IMPORTANT INFORMATION ON BACK


ISOFLURANE ICSC: 1435
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID

PHYSICAL DANGERS:
The vapour is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen.

CHEMICAL DANGERS:
On contact with hot surfaces or flames this substance decomposes forming corrosive fumes such as phosgene hydrogen chloride and hydrogen fluoride.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: IIb (not established but data is available) (DFG 2005).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyesand the skin. The vapour is irritating to the respiratory tract. The substance may cause effects on the central nervous system and cardiovascular system. Exposure at high levels may result in unconsciousness.

PHYSICAL PROPERTIES
Boiling point: 48.5C
Relative density (water = 1): 1.5
Solubility in water: poor
Vapour pressure, kPa at 20C: 32
Relative density of the vapour/air-mixture at 20C (air = 1): 1.2
Octanol/water partition coefficient as log Pow: 2.1
ENVIRONMENTAL DATA

NOTES
Check oxygen content before entering area. High concentrations in the air cause a deficiency of oxygen with the risk of unconsciousness or death. Forane is a trade name.
Card has been partly updated in April 2005. See sections Physical properties, Occupational Exposure Limits.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2004