• Cannabis sativa L. plant species carry more than 80 different naturally occurring compounds known as cannabinoids, including CBD (cannabidiol) and THC (tetrahydrocannabinol)(1). 
  • In a study involving individuals with alopecia (hair loss), subjects reported a 93.5% increase in hair regrowth after six months of CBD-rich hemp extract administration, without reported adverse effects(2).  
  • CBD topicals are a safer option(3) since cannabidiol in CBD topicals like hair and scalp care products are not absorbed into the entire body. Still, talking to a doctor is necessary when considering CBD oil for hair loss.
  •  A 2021 study showed that the effects of CBD-rich hemp on hair growth may be dependent on the CBD dose(4). 

What Is CBD and How Does It Work?

CBD (cannabidiol) is an active constituent of marijuana (cannabis). Although CBD is a vital element of medical marijuana, it comes from the hemp plant, a relative of marijuana(5). 

CBD and the Endocannabinoid System

CBD interacts with the ECS (endocannabinoid system). The ECS is present in almost every part of the body, maintaining homeostasis(6).  

Homeostasis is the process where biological systems maintain stability while adapting to conditions that are necessary for survival(7).

The ECS comprises vital components including cannabinoid receptors (CB1 and CB2 receptors) found in cells throughout the body(8).    

CB1 receptors play an indispensable role in pain sensation, whereas CB2 stimulates an inflammatory response that fights inflammation(9).

Cannabidiol has a low binding affinity for the two cannabinoid receptors. However, this non-psychoactive compound may antagonize them in the presence of THC(10). 

THC (tetrahydrocannabinol) is the mind-altering chemical found in marijuana(11). CBD may lessen the efficacy and potency of THC(12).  

Potential Benefits of CBD for Hair Loss

The most common form of hair loss is androgenetic alopecia (AGA), also known as male-pattern baldness among men(13). 

Hair is lost in a distinct pattern that usually begins above the temples. Hair may also thin at the crown and then progress to partial or total baldness. 

In women, however, AGA rarely leads to complete baldness. Generally, women’s hair becomes thinner all over the head. The hairline does not recede(14).  

According to a 2021 research article, the effects of CBD on hair growth may be dose-dependent(15). 

The study involved 35 subjects with androgenic alopecia. The researchers used a once-daily topical hemp oil formulation, averaging 3 mg to 4mg of CBD per day, together with other cannabinoids for six months.

The results showed that all subjects had some hair regrowth, with men showing slightly more improvement than women(16). In addition, the vertex area showed more hair regrowth than the temporal areas.

On average, about a 93.5% increase in hair was recorded after six months of CBD-rich hemp extract administration, without adverse effects reported(17).

AGA’s prevalence in men and women increases with age. Generally, it is the most common cause of hair loss due to baldness and hair thinning(18).

CBD Oil May Improve Blood Circulation

A study led by the researchers from the University College London (UCL) suggested that a single dose of CBD may help increase blood flow to the brain’s hippocampus(19). 

Hippocampus is a vital area of the brain associated with emotion and memory. 

A research study from Massachusetts General Hospital (MGH) hypothesized that blood vessels may hold an essential key to thicker hair growth(20).     

CBD Oil May Support Homeostasis

Homeostasis is a self-regulating process where living things maintain stability while adapting to changing environments. 

A disruption of homeostatic mechanisms leads to diseases. Effective therapy must be administered toward re-establishing homeostatic conditions(21).  

The endocannabinoid system regulates other systems within the body. The ECS consists of enzymes, cannabinoids, and cannabinoid receptors.

Activated cannabinoid receptors relay messages throughout the body and ensure homeostasis is achieved and maintained(22). 

Plant-based cannabinoids (phytocannabinoids) like CBD and THC mimic the action of compounds found in the body(23). Thus, the cannabis plant essentially functions as a mass stimulation to the endocannabinoid system. 

Due to the stimulation of cannabinoid receptors, the body treats phytocannabinoids, such as CBD and THC, as endocannabinoids naturally produced by the body(24). 

Although cannabidiol may not activate cannabinoid receptors, it may moderately inhibit the degradation of anandamide(25). Anandamide is an endocannabinoid in the human body that may control pain stimuli(26).

CBD Oil May Help Reduce Issues Induced by Hair Loss

Studies show that CBD’s anti-inflammatory effects may help with skin conditions, including psoriasis, eczema, and pruritus, like scalp pruritus (itchy scalp)(27).

Scalp pruritus is commonly reported in people with cicatricial alopecia(28). Cicatricial alopecia is an inflammatory condition where hair follicles are destroyed, leading to scarring or permanent hair loss(29). 

More Reasons to Use CBD Oil for Healthy Hair

Cannabidiol ‘s purported antioxidative and anti-inflammatory properties(30) may help with hair loss and promote healthy hair.

A study from the Journal of Medicine and Life indicated that a decreased total antioxidant activity and increased malondialdehyde levels in plasma samples of patients with androgenetic alopecia may be indicators of oxidative stress(31).  

Malondialdehyde is a biomarker of oxidative stress(32). 

A 2020 study from the journal Antioxidants suggested that CBD may affect redox balance by modifying the activity and level of both antioxidants and oxidants(33). 

CBD may also interrupt free radical chain reactions, capturing them or transforming them into less active forms(34). Free radicals are molecular species that may damage cells(35).

The body has endogenous defense mechanisms, including antioxidative properties that protect itself from free radicals(36). 

Like the skin, the hair follicles are also subject to aging. Free radicals may damage these hair follicles, decreasing hair pigmentation and hair production(37). 

A study mentioned that CBD may bind to amino acids through a hydrogen bond(38). Amino acids are the building blocks of proteins(39).

A study from the Journal of Cosmetic Science explained the function and interaction of some amino acids in hair care application(40). 

When incorporated in a hair conditioner, amino acids may improve bleach-damaged hair and enhance the color-retention of dyed hair. 

Individuals may also benefit from hempseed oil, used as a carrier oil in most CBD hemp oil products. 

Hemp oil is a term also used to refer to CBD oil. Hemp oil is an essential oil that comes from the flowers and leaves of hemp plants. 

On the other hand, hempseed oil is derived from the pressed seeds of hemp plants. Hempseed oil is packed with nutrients and essential fatty acids despite lacking CBD(41).  

Research from the Journal of Cosmetic Dermatology showed that a six-month supplementation with omega-3 and omega-6 fatty acids and antioxidants may act efficiently against hair loss(42).   

People with dry, itchy scalp may also use CBD oil products to reduce inflammation and itchiness(43). 

Preclinical evidence suggested that topical CBD application may help with skin disorders like eczema (atopic dermatitis), a condition that makes a portion of the skin red and itchy(44). 

A study from the Journal of Clinical Investigation suggested that CBD may help reduce sebum production(45). Hence, CBD hair products may also be used by people with greasy hair.  

Regardless of hair type, consumers must consult their physicians before using CBD oil for hair loss or using CBD products to ensure safety. 

How to Use CBD for Hair Loss

CBD products in several forms and concentrations are available in the market for nourishing and styling hair and moisturizing dry scalp. 

There are CBD edibles like gummies and capsules, topicals like creams and hair serums, and CBD-infused hair products like shampoos and conditioners. 

Also available are CBD products that specifically target dandruff and promote scalp health. Consumers may choose broad-spectrum, full-spectrum, or pure CBD products. 

Full-spectrum contains all extracts of the cannabis plant with less than 0.3% THC content. Meanwhile, broad-spectrum is almost the same as full-spectrum but almost THC-free. Lastly, CBD isolates are pure CBD. 

Side Effects of Using CBD Oil for Hair Loss

Most CBD brands aim to offer the best CBD products in the market. Nevertheless, the FDA (Food and Drug Administration) does not recognize CBD as a medical treatment. 

Some CBD users may experience minor side effects like dry mouth, reduced appetite, diarrhea, fatigue, and drowsiness(46). However, CBD is generally safe(47).  

Compared to other forms, ingredients of CBD topicals are not absorbed into the entire body, making them a safer option(48). 

FAQs

1. What nutrients are good for hair?

Omega 3 and 6 fatty acids, including antioxidants, may help with hair loss(49). 

Vitamin E may also benefit hair. A study from Tropical Life Science Research showed that individuals with hair loss reported a 34.5% improvement in hair growth after supplementing with tocotrienol (vitamin E) for eight months(50).

Vitamin E is a fat-soluble antioxidant(51) widely used in skincare products. 

Meanwhile, calcium plays a significant role in keeping hair healthy. It is an essential nutrient for healthy hair growth(52). 

On the other hand, vitamin A is vital in hair follicles as a deficiency, and excess vitamin A may lead to hair loss(53).  

2. Can someone put CBD oil on their scalp?

Yes. However, as with any new product, CBD users should do patch testing by applying a small amount of CBD on their arms to test for an allergic reaction. 

3. Can CBD oil treat thinning hair? 

Although CBD has purported health benefits, it cannot treat thinning hair. However, research shows CBD may help with hair growth, and the effects depend on the dose(54). 


  1. FDA and Cannabis: Research and Drug Approval Process
    https://www.fda.gov/news-events/public-health-focus/fda-and-cannabis-research-and-drug-approval-process
  2. Hair Regrowth With Cannabidiol (CBD)-Rich Hemp Extract –A Case Series
    https://publications.sciences.ucf.edu/cannabis/index.php/Cannabis/article/view/78/47
  3. How to Safely Use CBD: Should You Inhale, Spray, Apply, or Eat It?
    https://www.consumerreports.org/cbd/how-to-use-cbd-inhale-spray-apply-eat/
  4. Hair Regrowth With Cannabidiol (CBD)-Rich Hemp Extract –A Case Series
    https://publications.sciences.ucf.edu/cannabis/index.php/Cannabis/article/view/78/47
  5. Cannabidiol (CBD)-What We Know and What We Don’t
    https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
  6. The Endocannabinoid System, Our Universal Regulator
    https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator
  7. Homeostasis: The Underappreciated and Far Too Often Ignored Central Organizing Principle of Physiology
    https://www.frontiersin.org/articles/10.3389/fphys.2020.00200/full
  8. The Endocannabinoid System, Our Universal Regulator
    https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator
  9. Cannabinoids and Pain: New Insights From Old Molecules
    https://www.frontiersin.org/articles/10.3389/fphar.2018.01259/full
  10. Ibid.
  11. What Is Marijuana?
    https://www.drugabuse.gov/publications/research-reports/marijuana/what-marijuana
  12. Cannabinoids and Pain: New Insights From Old Molecules
    https://www.frontiersin.org/articles/10.3389/fphar.2018.01259/full
  13. Androgenetic Alopecia
    https://medlineplus.gov/genetics/condition/androgenetic-alopecia/
  14. Ibid.
  15. Hair Regrowth With Cannabidiol (CBD)-Rich Hemp Extract –A Case Series
    https://publications.sciences.ucf.edu/cannabis/index.php/Cannabis/article/view/78/47
  16. Ibid.
  17. Ibid.
  18. Hair Regrowth With Cannabidiol (CBD)-Rich Hemp Extract –A Case Series
    https://publications.sciences.ucf.edu/cannabis/index.php/Cannabis/article/view/78/47
  19. Cannabidiol Improves Blood Flow to the Brain’s Hippocampus
    https://www.ucl.ac.uk/news/2020/aug/cannabidiol-improves-blood-flow-brains-hippocampus
  20. Blood Vessels Hold Key To Thicker Hair Growth
    https://www.sciencedaily.com/releases/2001/02/010215074636.htm
  21. Homeostasis: The Underappreciated and Far Too Often Ignored Central Organizing Principle of Physiology
    https://www.frontiersin.org/articles/10.3389/fphys.2020.00200/full
  22. The Endocannabinoid System, Our Universal Regulator
    https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator
  23. Ibid.
  24. Ibid.
  25. Cannabidiol Enhances Anandamide Signaling and Alleviates Psychotic Symptoms of Schizophrenia
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316151/
  26. The Endocannabinoid System, Our Universal Regulator
    https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator
  27. Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736837/
  28. Scalp Pruritus: Review of the Pathogenesis, Diagnosis, and Management
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350598/
  29. Cicatricial (Scarring) Alopecia
    https://www.mountsinai.org/care/dermatology/services/hair-nails/cicatricial-alopecia
  30. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/
  31. Oxidative Stress in Androgenetic Alopecia
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152608/
  32. Reliability of Malondialdehyde as a Biomarker of Oxidative Stress in Psychological Disorders
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597159/
  33. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/
  34. Ibid.
  35. Free Radicals, Antioxidants in Disease and Health
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614697/
  36. Oxidative Stress in Ageing of Hair
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929555/
  37. Ibid.
  38. Antioxidative and Anti-Inflammatory Properties of Cannabidiol
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/
  39. Amino Acid: Building Block Models – In Brief
    https://cbm.msoe.edu/teacherWorkshops/mmwResources/documents/molymodBrief.pdf
  40. Hair and Amino Acids: The Interactions and the Effects
    https://pubmed.ncbi.nlm.nih.gov/17728935/
  41. Hemp Seed Oil Properties
    https://extension.okstate.edu/fact-sheets/hemp-seed-oil-properties.html
  42. Effect of a Nutritional Supplement on Hair Loss in Women
    https://onlinelibrary.wiley.com/doi/10.1111/jocd.12127
  43. Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736837/
  44. Ibid.
  45. Cannabidiol Exerts Sebostatic and Antiinflammatory Effects on Human Sebocytes
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151231/
  46. What Are the Benefits of CBD — And Is It Safe to Use?
    https://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/is-cbd-safe-and-effective/faq-20446700
  47. Cannabidiol (CBD)
    https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  48. How to Safely Use CBD: Should You Inhale, Spray, Apply, or Eat It?
    https://www.consumerreports.org/cbd/how-to-use-cbd-inhale-spray-apply-eat/
  49. Effect of a Nutritional Supplement on Hair Loss in Women
    https://onlinelibrary.wiley.com/doi/10.1111/jocd.12127
  50. Effects of Tocotrienol Supplementation on Hair Growth in Human Volunteers
    https://pubmed.ncbi.nlm.nih.gov/24575202/
  51. Vitamin E
    https://ods.od.nih.gov/factsheets/VitaminE-HealthProfessional/
  52. Nutrition of Women With Hair Loss Problem During the Period of Menopause
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828511/
  53. Dietary Vitamin A Regulates Wingless-Related Mmtv Integration Site Signaling to Alter the Hair Cycle
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803037/
  54. Hair Regrowth with Cannabidiol (CBD)-rich Hemp Extract –A Case Series
    https://publications.sciences.ucf.edu/cannabis/index.php/Cannabis/article/view/78/47
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