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HEXAMETHYLENETETRAMINE ICSC: 1228
Date of Peer Review: March 2002

1,3,5,7-Tetraazaadamantane
Methenamine
Hexamine
1,3,5,7-Tetraazatricyclo(3.3.1.1(3,7))decane
CAS # 100-97-0 C6H12N4
RTECS # MN4725000 Molecular mass: 140.2
UN # 1328
EC # 612-101-00-2
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Foam, water spray, powder.
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE
PREVENT DISPERSION OF DUST!

Inhalation Cough.
Local exhaust or breathing protection.
Fresh air, rest. Refer for medical attention.
Skin Redness. Pain.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes Redness. Pain.
Face shield or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Abdominal pain. Nausea. Vomiting.
Do not eat, drink, or smoke during work.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water. Personal protection: A/P2 filter respirator for organic vapour and harmful dust.
EU Classification
Symbol: F, Xn
R: 11-42/43
S: (2-)-16-22-24-37
UN Classification
UN Hazard Class: 4.1
UN Pack Group: III
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-41S1328
Separated from strong acids and strong oxidants. Dry.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 1999

SEE IMPORTANT INFORMATION ON BACK
HEXAMETHYLENETETRAMINE ICSC: 1228
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
HYGROSCOPIC, COLOURLESS CRYSTALS OR WHITE CRYSTALLINE POWDER

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air.

CHEMICAL DANGERS:
The substance decomposes on heating or on burning producing toxic and corrosive gases including formaldehyde, ammonia, hydrogen cyanide and nitrogen oxides. The solution in water is a weak base. Reacts with strong oxidants and strong acids producing toxic and corrosive gases. Attacks aluminium and zinc.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: IIb (not established but data is available); sensitization of skin (Sh); (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

INHALATION RISK:
Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is mildly irritating to the eyes and the skin.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation exposure may cause asthma.
PHYSICAL PROPERTIES
Sublimation point: about 260C
Density: 1.33 g/cm
Solubility in water: good
Relative vapour density (air = 1): 4.9
Flash point: 250C c.c.
Auto-ignition temperature: 390C
Octanol/water partition coefficient as log Pow: -2.84
ENVIRONMENTAL DATA

NOTES
The substance may release formaldehyde. See ICSC 0695 Formaldehyde.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact. The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
Card has been partly updated in April 2005. See section Occupational Exposure Limits.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 1999