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2,3,4,6-TETRACHLOROPHENOL ICSC: 1089
Date of Peer Review: October 2005

2,4,5,6-Tetrachlorophenol
Phenol, 2,3,4,6-tetrachloro-
CAS # 58-90-2 C6H2Cl4O
RTECS # SM9275000 Molecular mass: 231.9
UN # 2020
EC Index # 604-013-00-8
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Water spray. Alcohol-resistant foam. Dry powder. Carbon dioxide.
EXPLOSION


EXPOSURE
PREVENT DISPERSION OF DUST!

Inhalation Cough. Shortness of breath. Convulsions.
Local exhaust or breathing protection.
Fresh air, rest. Refer for medical attention.
Skin MAY BE ABSORBED! Redness.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes Redness. Pain.
Safety goggles.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Abdominal pain. Diarrhoea. Headache. Dizziness. Vomiting. Weakness. Convulsions. Muscular spasms. Increased body temperature and sweating (see Notes).
Do not eat, drink, or smoke during work. Wash hands before eating.
Give a slurry of activated charcoal in water to drink. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Personal protection: P2 filter respirator for harmful particles. Chemical protection suit. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers.
Do not transport with food and feedstuffs.
EU Classification
Symbol: T, N
R: 25-36/38-50/53
S: (1/2-)-26-28-37-45-60-61
UN Classification
UN Hazard Class: 6.1
UN Pack Group: III
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-61S2020 or 61GT2-III
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Store in an area without drain or sewer access.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
2,3,4,6-TETRACHLOROPHENOL ICSC: 1089
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
BROWN SOLID IN VARIOUS FORMS, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS:
The substance decomposes on heating producing corrosive fumes including hydrogen chloride.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established. MAK not established.
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

INHALATION RISK:
A harmful concentration of airborne particles can be reached quickly when dispersed.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes, the skin and the respiratory tract. See Notes.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the liver. The substance may have effects on the skin, resulting in chloracne. (See Notes.)
PHYSICAL PROPERTIES
Melting point: 70C
Density: 1.8 g/cm
Solubility in water, g/100 ml at 20C: 0.1 (very poor)
Flash point: 100C
Octanol/water partition coefficient as log Pow: 4.45
ENVIRONMENTAL DATA
The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur in fish.
NOTES
2,3,4,6-Tetrachlorophenol is a polychlorophenol which, as a group, has been classified by IARC (1999) as possibly carcinogenic to humans, but the data on this specific substance are inconclusive. No data are available on this isomer but a mixture of tetrachlorophenols may cause irritation of the skin, eyes and respiratory tract. These substances may cause acute metabolic effects resulting in damage in several organs notably in central nervous system. Some technical products may contain highly toxic impurities including polychlorinated dibenzo-p-dioxins and -furans. Depending on the degree of exposure, periodic medical examination is suggested.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005