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TRIMETHYL PHOSPHATE ICSC: 0686
Date of Peer Review: October 2004

Phosphoric acid trimethyl ester
Trimethyl orthophosphate
CAS # 512-56-1 C3H9O4P / (CH3O)3PO
RTECS # TC8225000 Molecular mass: 140.1
UN #
EC Index #
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Alcohol-resistant foam, dry powder, carbon dioxide water spray.
EXPLOSION


EXPOSURE
AVOID ALL CONTACT!

Inhalation Cough. Sore throat.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Refer for medical attention.
Skin Redness.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
Eyes Redness.
Safety goggles.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Shortness of breath. Weakness. Hyperirritability. Tremors.
Do not eat, drink, or smoke during work.
Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Personal protection: chemical protection suit including self-contained breathing apparatus.
EU Classification
UN Classification

EMERGENCY RESPONSE STORAGE

Separated from strong oxidants, strong bases.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
TRIMETHYL PHOSPHATE ICSC: 0686
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID.

CHEMICAL DANGERS:
The substance decomposes on burning producing toxic fumes including phosphorous oxides. Reacts with strong bases and strong oxidants. May explode on heating during large scale atmospheric pressure distillation.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: skin absorption (H); Carcinogen category: 3B; Germ cell mutagen group: 2; (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.

INHALATION RISK:
No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes, the skin and the respiratory tract. The substance may cause effects on the nervous system.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the nervous system, resulting in flaccid paralysis. May cause heritable genetic damage to human germ cells.
PHYSICAL PROPERTIES
Boiling point: 197.2C
Melting point: -46C
Relative density (water = 1): 1.2
Solubility in water, g/100 ml at 25C: 50 (good)
Vapour pressure, kPa at 20C: 0.11
Flash point: 107C
Octanol/water partition coefficient as log Pow: -0.52 and -0.78
ENVIRONMENTAL DATA

NOTES

ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005