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TRICHLOROACETIC ACID ICSC: 0586
Date of Peer Review: November 1998

Trichloroethanoic acid
Aceto-caustin
TCA
CAS # 76-03-9 C2HCl3O2 / CCl3COOH
RTECS # AJ7875000 Molecular mass: 163.4
UN # 1839
EC Index # 607-004-00-7
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

In case of fire in the surroundings: use appropriate extinguishing media.
EXPLOSION


EXPOSURE
AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
Inhalation Sore throat. Cough. Burning sensation. Headache. Nausea. Vomiting. Shortness of breath. Laboured breathing. Symptoms may be delayed (see Notes).
Ventilation (not if powder), local exhaust, or breathing protection.
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Skin Pain. Redness. Blisters. Skin burns.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes Pain. Redness. Severe deep burns.
Face shield or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Burning sensation. Abdominal pain. Shock or collapse.
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink. Rest. Refer for medical attention. See Notes.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Sweep spilled substance into water filled containers; if appropriate, moisten first to prevent dusting. Cautiously neutralize remainder with alkali such as sodium bicarbonate, sodium hydroxide. Then wash away with plenty of water. Personal protection: complete protective clothing including self-contained breathing apparatus.
Unbreakable packaging; put breakable packaging into closed unbreakable container.
EU Classification
Symbol: C, N
R: 35-50/53
S: (1/2-)-26-36/37/39-45-60-61
UN Classification
UN Hazard Class: 8
UN Pack Group: II
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-80GC4-II+III
Separated from food and feedstuffs. See Chemical Dangers. Cool. Dry. Well closed. Keep in a well-ventilated room.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
TRICHLOROACETIC ACID ICSC: 0586
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS HYGROSCOPIC CRYSTALS, WITH PUNGENT ODOUR.

CHEMICAL DANGERS:
The substance decomposes on heating producing toxic and corrosive fumes including hydrogen chloride and chloroform. The solution in water is a strong acid, it reacts violently with bases and is corrosive to many metals.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 1 ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2005).
MAK: IIb (not established but data is available); (DFG 2005).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

INHALATION RISK:
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is corrosive to the eyes, the skin and the respiratory tract. Corrosive on ingestion. Inhalation of vapour may cause lung oedema (see Notes). The effects may be delayed. Medical observation is indicated.

PHYSICAL PROPERTIES
Boiling point: 198C
Melting point: 58C
Density: 1.6 g/cm
Solubility in water: very good
Vapour pressure, Pa at 51C: 133
Relative vapour density (air = 1): 5.6
Octanol/water partition coefficient as log Pow: 1.7
ENVIRONMENTAL DATA

NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. Card has been partly updated in October 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005