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METHYL ACETATE ICSC: 0507
Date of Peer Review: October 1997

Acetic acid methyl ester
CAS # 79-20-9 C3H6O2 / CH3COOCH3
RTECS # AI9100000 Molecular mass: 74.1
UN # 1231
EC Index # 607-021-00-X
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Highly flammable.
NO open flames, NO sparks, and NO smoking.
Powder, AFFF, foam, carbon dioxide.
EXPLOSION Vapour/air mixtures are explosive.
Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE


Inhalation Cough. Drowsiness. Dullness. Headache. Laboured breathing. Sore throat. Unconsciousness. Symptoms may be delayed (see Notes).
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Skin Dry skin. Redness. Roughness.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes Redness. Pain. Blurred vision.
Safety goggles, or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Abdominal pain. Nausea. Vomiting. Weakness. (Further see Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Give plenty of water to drink. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. Personal protection: self-contained breathing apparatus.
EU Classification
Symbol: F, Xi
R: 11-36-66-67
S: (2-)-16-26-29-33
Note: [6]
UN Classification
UN Hazard Class: 3
UN Pack Group: II
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-30S1231
NFPA Code: H1; F3; R0;
Fireproof. Separated from strong oxidants, acids. Cool. Keep in the dark. Well closed.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
METHYL ACETATE ICSC: 0507
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
The vapour is heavier than air and may travel along the ground; distant ignition possible.

CHEMICAL DANGERS:
The substance decomposes on heating under influence of air, bases, strong oxidants, UV-light, causing fire and explosion hazard. The substance is a strong reducing agent and reacts with oxidants. Attacks many metals in presence of water. Attacks plastic.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 200 ppm as TWA; 250 ppm as STEL; (ACGIH 2004).
MAK: 100 ppm, 310 mg/m; Peak limitation category: I(4); Pregnancy risk group: C; (DFG 2005).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the eyes and the respiratory tract. The substance may cause effects on the central nervous system, resulting in lowering of consciousness. Exposure far above the OEL may result in death.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The liquid defats the skin. The substance may have effects on the optic nerve, resulting in impaired vision.
PHYSICAL PROPERTIES
Boiling point: 57C
Melting point: -98C
Relative density (water = 1): 0.93
Solubility in water, g/100 ml at 20C: 24.4
Vapour pressure, kPa at 20C: 21.7
Relative vapour density (air = 1): 2.6
Relative density of the vapour/air-mixture at 20C (air = 1): 1.3
Flash point: -13C c.c.
Auto-ignition temperature: 455C
Explosive limits, vol% in air: 3.1-16
Octanol/water partition coefficient as log Pow: 0.18
ENVIRONMENTAL DATA

NOTES
The symptoms of damage to the optical nerve do not become manifest until a few hours have passed. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. The odour warning when the exposure limit value is exceeded is insufficient. Devoton, Tereton are trade names.
Card has been partly updated in October 2004 and 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005