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N,N-DIMETHYLACETAMIDE ICSC: 0259
Date of Peer Review: September 1993

Acetic acid dimethylamide
Dimethylacetamide
CAS # 127-19-5 CH3CON(CH3)2
RTECS # AB7700000 Molecular mass: 87.1
UN #
EC Index # 616-011-00-4
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION Above 70C explosive vapour/air mixtures may be formed.
Above 70C closed system, ventilation, and explosion-proof electrical equipment.

EXPOSURE
STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN!

Inhalation Headache. Nausea. Vomiting.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.
Skin MAY BE ABSORBED! Redness. (Further see Inhalation).
Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes VAPOUR WILL BE ABSORBED! Redness. Pain.
Face shield.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Abdominal cramps. Diarrhoea. (Further see Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Give plenty of water to drink. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place.
EU Classification
Symbol: T
R: 61-20/21
S: 53-45
UN Classification

EMERGENCY RESPONSE STORAGE
NFPA Code: H 2; F 2; R 0;
Well closed. Ventilation along the floor.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
N,N-DIMETHYLACETAMIDE ICSC: 0259
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
OILY, COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS:
The substance decomposes on heating producing toxic fumes (nitrogen oxides). Attacks many plastics.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 10 ppm as TWA; (skin); A4 (not classifiable as a human carcinogen); (ACGIH 2004).
MAK: 10 ppm, 36 mg/m; Peak limitation category: II(2); skin absorption (H); Pregnancy risk group: C; (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and through the skin.

INHALATION RISK:
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes and the skin.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The liquid defats the skin. The substance may have effects on the central nervous system and liver.
PHYSICAL PROPERTIES
Boiling point: 165C
Melting point: -20C
Relative density (water = 1): 0.94
Solubility in water: miscible
Vapour pressure, kPa at 20C: 0.33
Relative vapour density (air = 1): 3.01
Relative density of the vapour/air-mixture at 20C (air = 1): 1.01
Flash point: 70C (o.c.)
Auto-ignition temperature: 490C
Explosive limits, vol% in air: 1.8 (at 100C) - 11.5 (at 160C)
Octanol/water partition coefficient as log Pow: -0.77
ENVIRONMENTAL DATA
This substance may be hazardous to the environment; special attention should be given to soil contaminationl.
NOTES
Use of alcoholic beverages enhances the harmful effect. Depending on the degree of exposure, periodic medical examination is suggested. No odour warning if toxic concentrations are present. Absorption through the skin proceeds very quickly. Most types of protective gloves are not entirely effective. Card has been partly updated in October 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005