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CYCLOHEXIMIDE ICSC: 0244
Date of Peer Review: April 1997

4-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)
2,6-Piperidinedione
CAS # 66-81-9 C15H23NO4
RTECS # MA4375000 Molecular mass: 281.35
UN # 2588
EC Index # 613-140-00-8
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Gives off irritating or toxic fumes (or gases) in a fire.

In case of fire in the surroundings: use appropriate extinguishing media.
EXPLOSION


EXPOSURE
PREVENT DISPERSION OF DUST! STRICT HYGIENE!

Inhalation
Local exhaust or breathing protection.
Fresh air, rest.
Skin Redness. Pain.
Protective gloves.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes Redness. Pain.
Safety spectacles.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Diarrhoea. Unconsciousness. See Notes.
Do not eat, drink, or smoke during work.
Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Do NOT wash away into sewer. Sweep spilled substance into sealable containers. Carefully collect remainder, then remove to safe place. Personal protection: P2 filter respirator for harmful particles.
Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs.
EU Classification
Symbol: T+, N
R: 61-28-51/53-68
S: 53-45-61
UN Classification
UN Hazard Class: 6.1
UN Pack Group: I
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-61GT7-I
Separated from food and feedstuffs. Well closed. Keep in a well-ventilated room.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
CYCLOHEXIMIDE ICSC: 0244
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS CRYSTALS.

CHEMICAL DANGERS:
The substance decomposes on heating producing toxic and corrosive fumes including nitrogen oxides.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK:
Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the eyes and the skin. Exposure may result in death. See Notes.

PHYSICAL PROPERTIES
Melting point: 119.5-121C
Solubility in water, g/100 ml at 2C: 2.1
Octanol/water partition coefficient as log Pow: 0.55
ENVIRONMENTAL DATA
This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal.
NOTES
Depending on the degree of exposure, periodic medical examination is suggested. Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken. Animal studies have indicated that the substance may be very toxic by ingestion. Hizarocin, Acti-dione, Acti-aid, Naramycin, Naramycin A and Neocycloheximide are trade names. Card has been partly updated in October 2005. See sections EU classification, Emergency Response.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005