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BENZIDINE ICSC: 0224
Date of Peer Review: March 1995

(1,1'-Biphenyl)-4,4'-diamine
4,4'-Diaminobiphenyl
p-Diaminodiphenyl
CAS # 92-87-5 C12H12N2 / NH2C6H4-C6H4NH2
RTECS # DC9625000 Molecular mass: 184.2
UN # 1885
EC Index # 612-042-00-2
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible. See Notes. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, carbon dioxide.
EXPLOSION


EXPOSURE
AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
Inhalation
Closed system and ventilation.
Fresh air, rest. Refer for medical attention.
Skin MAY BE ABSORBED!
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes
Face shield or eye protection in combination with breathing protection if powder.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place.
Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs.
EU Classification
Symbol: T, N
R: 45-22-50/53
S: 53-45-60-61
Note: [E]
UN Classification
UN Hazard Class: 6.1
UN Pack Group: II
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-61GT2-II
Separated from strong oxidants, food and feedstuffs. Keep in the dark. Well closed.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
BENZIDINE ICSC: 0224
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
WHITE OR REDDISH CRYSTALLINE POWDER, TURNS DARK ON EXPOSURE TO AIR AND LIGHT.

CHEMICAL DANGERS:
The substance decomposes on heating and on burning producing toxic fumes including nitrogen oxides. Reacts violently with strong oxidants, especially nitric acid.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: (skin) A1 (confirmed human carcinogen); (ACGIH 2004).
MAK: skin absorption (H); Carcinogen category: 1; (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

INHALATION RISK:
Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
This substance is carcinogenic to humans.
PHYSICAL PROPERTIES
Boiling point: 401C
Melting point: (see Notes) 128C
Relative density (water = 1): 1.25
Solubility in water: none
Relative vapour density (air = 1): 6.36
Octanol/water partition coefficient as log Pow: 1.34
ENVIRONMENTAL DATA
The substance is toxic to aquatic organisms.
NOTES
Given melting point when anhydrous and rapidly heated, when slowly heated: 115-120C. Addition of small amounts of a flammable substance or an increase in the oxygen content of the air strongly enhances combustibility. Card has been partly updated in October 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005