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ISOPROPYL GLYCIDYL ETHER ICSC: 0171
Date of Peer Review: November 1998

1,2-Epoxy-3-isopropoxypropane
IGE
(Isopropoxymethyl)oxirane
CAS # 4016-14-2 C6H12O2
RTECS # TZ3500000 Molecular mass: 116.2
UN # 1993
EC #
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Flammable.
NO open flames, NO sparks, and NO smoking.
Powder, AFFF, foam, carbon dioxide.
EXPLOSION Above 33C explosive vapour/air mixtures may be formed.
Above 33C use a closed system, ventilation, and explosion-proof electrical equipment.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
PREVENT GENERATION OF MISTS!

Inhalation Burning sensation. Cough. Dizziness. Headache. Laboured breathing. Shortness of breath. Sore throat. Symptoms may be delayed (see Notes).
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Half-upright position. Refer for medical attention.
Skin Redness. Pain.
Protective gloves.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain.
Safety spectacles or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion
Do not eat, drink, or smoke during work.
Rinse mouth. Give plenty of water to drink.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Collect leaking and spilled liquid in sealable containers as far as possible. Carefully collect remainder, then remove to safe place. Personal protection: filter respirator for organic gases and vapours.
EU Classification
UN Classification
UN Hazard Class: 3
UN Pack Group: III
EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-30GF1-III
Fireproof. Separated from strong oxidants, acids. Cool. Dry. Keep in the dark. Well closed.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2004

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ISOPROPYL GLYCIDYL ETHER ICSC: 0171
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID

CHEMICAL DANGERS:
The substance can presumably form explosive peroxides upon exposure to air or light. Reacts violently with strong oxidants amines and acids.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 50 ppm as TWA, 75 ppm as STEL; (ACGIH 2004).
MAK: Carcinogen category: 3B; (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes, the skin and the respiratory tract. Inhalation of vapour may cause lung oedema (see Notes). The substance may cause effects on the central nervous system. Exposure above the OEL could cause lowering of consciousness.

PHYSICAL PROPERTIES
Boiling point: 137C
Relative density (water = 1): 0.92
Solubility in water, g/100 ml: 19
Vapour pressure, kPa at 25C: 1.25
Relative vapour density (air = 1): 4.15
Relative density of the vapour/air-mixture at 20C (air = 1): 1.04
Flash point: 33C c.c.
Explosive limits, vol% in air: see Notes
Octanol/water partition coefficient as log Pow: 0.5
ENVIRONMENTAL DATA

NOTES
Explosive limits are unknown in literature, although the substance is combustible and has a flash point < 61C. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. Check for peroxides prior to distillation; eliminate if found.
Card has been partly updated in April 2005. See sections Occupational Exposure Limits, Emergency Response.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2004