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STRYCHNINE ICSC: 0197
Date of Peer Review: April 2000

Strychnidin-10-one
CAS # 57-24-9 C21H22N2O2
RTECS # WL2275000 Molecular mass: 334.4
UN # 1692
EC Index # 614-003-00-5
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO contact with oxidants.
In case of fire in the surroundings: use appropriate extinguishing media.
EXPLOSION


EXPOSURE
AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
Inhalation (See Ingestion).
Local exhaust or breathing protection.
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin
Protective gloves.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes
Safety goggles.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Convulsions. Muscle stiffness. Shock or collapse.
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Refer for medical attention. Keep victim completely undisturbed.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Do NOT let this chemical enter the environment. Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Personal protection: self-contained breathing apparatus.
Do not transport with food and feedstuffs. Marine pollutant.
EU Classification
Symbol: T+, N
R: 27/28-50/53
S: (1/2-)-36/37-45-60-61
UN Classification
UN Hazard Class: 6.1
UN Pack Group: I
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-61GT2-I
Provision to contain effluent from fire extinguishing. Separated from strong oxidants, food and feedstuffs. Well closed.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
STRYCHNINE ICSC: 0197
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
ODOURLESS AND COLOURLESS CRYSTALS, WITH BITTER TASTE.

CHEMICAL DANGERS:
The substance decomposes on heating producing toxic fumes including nitrogen oxides. The substance is a weak base. Reacts with strong oxidants, causing fire and explosion hazard.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.15 mg/m as TWA; (ACGIH 2004).
MAK: IIb (not established but data is available) (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

INHALATION RISK:
Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the central nervous system, resulting in convulsions, muscle contractions, respiratory failure. Exposure may result in death.

PHYSICAL PROPERTIES
Decomposes below boiling point
Melting point: 275-285C
Density: 1.36 g/cm
Solubility in water: none
Octanol/water partition coefficient as log Pow: 1.68
ENVIRONMENTAL DATA
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment; special attention should be given to birds. This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal.
NOTES
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Card has been partly updated in April 2005. See sections Occupational Exposure Limits, Emergency Response.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005
See Also:
        Strychnine (PIM 507)