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ROTENONE ICSC: 0944
Date of Peer Review: April 2000

Tubotoxine
Derris powder
CAS # 83-79-4 C23H22O6
RTECS # DJ2800000 Molecular mass: 394.45
UN # 2588
EC # 650-005-00-2
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible.
NO open flames.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION


EXPOSURE
PREVENT DISPERSION OF DUST! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!
IN ALL CASES CONSULT A DOCTOR!
Inhalation Confusion. Cough. Headache. Tremor. Laboured breathing. Nausea. Sore throat. Unconsciousness.
Local exhaust or breathing protection.
Fresh air, rest. Artificial respiration if indicated.
Skin Redness.
Protective gloves.
First rinse with plenty of water, then remove contaminated clothes and rinse again. Rinse and then wash skin with water and soap.
Eyes Redness.
Safety goggles, or eye protection in combination with breathing protection if powder.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Abdominal cramps. Convulsions. Diarrhoea. Vomiting. (Further see Inhalation).
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Rest. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Sweep spilled substance into air tight containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. (Extra personal protection: P3 filter respirator for toxic particles). Do NOT let this chemical enter the environment.
Do not transport with food and feedstuffs. Marine pollutant.
EU Classification
Symbol: T, N
R: 25-36/37/38-50/53
S: (1/2-)-22-24/25-36-45-60-61
UN Classification
UN Hazard Class: 6.1
UN Pack Group: III
EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT7-III
Separated from food and feedstuffs. Well closed.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2004

SEE IMPORTANT INFORMATION ON BACK


ROTENONE ICSC: 0944
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS CRYSTALS

CHEMICAL DANGERS:
The substance decomposes on burning producing irritating fumes.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 5 mg/m as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 2004).
MAK: IIb (not established but data is available); skin absorption (H); (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK:
Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the eyes, the skin and the respiratory tract. The substance may cause effects on the central nervous system, resulting in convulsions and respiratory depression.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the kidneys and liver.
PHYSICAL PROPERTIES
Decomposes below boiling point
Melting point: 165-166C
Density: 1.27 g/cm
Solubility in water: none
Octanol/water partition coefficient as log Pow: 4.10
ENVIRONMENTAL DATA
The substance is very toxic to aquatic organisms. Avoid release to the environment in circumstances different to normal use. The substance may cause long-term effects in the aquatic environment.
NOTES
The substance is combustible but no flash point is available in literature. Carrier solvents used in commercial formulations may change physical and toxicological properties. Depending on the degree of exposure, periodic medical examination is suggested.
Card has been partly updated in April 2005. See sections Emergency response, Occupational Exposure Limits.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2004
See Also:
        Rotenone (PIM 474)