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PROPOXUR ICSC: 0191
Date of Peer Review: October 1994

2-Isopropoxyphenyl methylcarbamate
Phenol, 2-(1-methylethoxy)-,methylcarbamate
2-(1-Methylethoxy)phenyl methylcarbamate
PHC
CAS # 114-26-1 C11H15NO3
RTECS # FC3150000 Molecular mass: 209.2
UN # 2757
EC Index # 006-016-00-4
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible under specific conditions. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Water spray, foam, powder, carbon dioxide.
EXPLOSION


EXPOSURE
PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!
IN ALL CASES CONSULT A DOCTOR!
Inhalation Dizziness. Headache. Sweating. Laboured breathing. Nausea. Unconsciousness. Vomiting. Pupillary constriction, muscle cramp, excessive salivation.
Local exhaust or breathing protection.
Fresh air, rest. Half-upright position. Refer for medical attention. See Notes.
Skin MAY BE ABSORBED! (Further see Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes Pupillary constriction. Blurred vision.
Safety spectacles or eye protection in combination with breathing protection if powder.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Abdominal cramps. Convulsions. Diarrhoea. Weakness. Muscle twitching. (Further see Inhalation).
Do not eat, drink, or smoke during work. Wash hands before eating.
Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention. See Notes.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Do NOT wash away into sewer. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Personal protection: complete protective clothing including self-contained breathing apparatus.
Do not transport with food and feedstuffs. Marine pollutant.
EU Classification
Symbol: T, N
R: 25-50/53
S: (1/2-)-37-45-60-61
UN Classification
UN Hazard Class: 6.1
UN Pack Group: III
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-61GT7-III
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
PROPOXUR ICSC: 0191
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
WHITE CRYSTALLINE POWDER.

CHEMICAL DANGERS:
The substance decomposes on heating or on burning producing toxic fumes including methylisocyanate, nitrogen oxides.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.5 mg/m as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued; (ACGIH 2004).
MAK: (Inhalable fraction) 2 mg/m; Peak limitation category: II(8); (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

INHALATION RISK:
Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the nervous system, liver, kidneys, resulting in respiratory failure, convulsions and tissue lesions. Cholinesterase inhibitor. Exposure may result in death.

PHYSICAL PROPERTIES
Melting point: 91C
Solubility in water, g/100 ml at 20C: 0.2 (poor)
Vapour pressure, Pa at 20C: 0.001
Octanol/water partition coefficient as log Pow: 1.52
ENVIRONMENTAL DATA
This substance may be hazardous to the environment; special attention should be given to mammals, birds, aquatic organisms, soil organisms and honey bees.
NOTES
Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvents also consult the ICSCs of these materials. Carrier solvents used in commercial formulations may change physical and toxicological properties. Baygon, Blattanex, Bolfo, Invisi-Gard, Isocarb, o-IMPC, Propyon, Rhoden, Sendran, Suncide, Tendex, Tugon Fliegenkugel, Unden, Undene are trade names. If the substance is present under the form of a formulation containing hydrocarbon solvents, vomiting may not be induced. Card has been partly updated in October 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005
See Also:
        Propoxur (PDS)