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SECTION 1. CHEMICAL IDENTIFICATION

CHEMINFO Record Number: 177
CCOHS Chemical Name: Polypropylene glycol monomethyl ether

Synonyms:
alpha-Methyl-omega-hydroxypoly-(oxy(methyl-1,2-ethanediyl))
Polypropylene glycol methyl ether
Poly(oxypropylene) monomethyl ether
Propylene oxide-methanol adduct
Ether monométhylique du polypropylèneglycol

Trade Name(s):
Dowfroth 1012 Flotation Frother
Dowfroth 250-C Floation Frother
Jeffox OL 2700
Slovasol 2430

CAS Registry Number: 37286-64-9
RTECS Number(s): TR4690000
Chemical Family: Aliphatic ether alcohol / aliphatic glycol ether / aliphatic poly glycol ether / aliphatic poly glycol mono ether / propylene glycol ether / polypropylene glycol monoether
Molecular Formula: (C3-H6-O)n.C-H4-O
Structural Formula: H(-O-C3H6-)x-O-CH3

SECTION 2. DESCRIPTION

Appearance and Odour:
Colourless to amber coloured liquid; odourless.(1,3,4)

Odour Threshold:
No information is available

Warning Properties:
No information is available for evaluation.

Uses and Occurrences:
Component of surfactants, lubricants, hydraulic fluids; water insoluble lubricant; flotation frother; solvent.


SECTION 3. HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW:
Colourless to amber, odourless liquid. Little or no hazard if spilled. Can probably burn if strongly heated.



POTENTIAL HEALTH EFFECTS

Effects of Short-Term (Acute) Exposure

Inhalation:
Polypropylene glycol monomethyl ether is not expected to produce vapours under normal conditions. Mists might be mildly irritating.

Skin Contact:
Based on similarity to other propylene glycol methyl ethers, polypropylene glycol monomethyl ether is not expected to be a skin irritant. Although skin absorption is likely, toxic amounts are not expected to be absorbed with normal handling and use.

Eye Contact:
No information available. Related materials, such as dipropylene glycol methyl ether and tripropylene glycol methyl ether, cause only mild temporary irritation with no corneal injury.

Ingestion:
Due to the very low oral toxicity shown in animal studies, it is very unlikely that toxic amounts would be ingested with normal use and handling.

Effects of Long-Term (Chronic) Exposure

No chronic effects have been reported. Based on similarity to other propylene glycol methyl ethers, none are expected.

Carcinogenicity:

No human or animal information is available.

The International Agency for Research on Cancer (IARC) has not evaluated the carcinogenicity of this chemical.

The American Conference of Governmental Industrial Hygienists (ACGIH) has no listing for this chemical.

The US National Toxicology Program (NTP) has not listed this chemical in its report on carcinogens.

Teratogenicity and Embryotoxicity:
Animal studies with the chemically related propylene glycol mono methyl ether have shown no reproductive effects. None are expected for polypropylene glycol mono methyl ether.

Reproductive Toxicity:
No human or animal information is available.

Mutagenicity:
No information is available.

Toxicologically Synergistic Materials:
No information is available

Potential for Accumulation:
Industrial exposure may occur by any of the common routes, but under normal conditions of use, the hazards would be expected to be minimal, except under the most adverse conditions. It is best to minimize contact/exposure until more information is available. Based on what is known about other propylene glycol ethers, polypropylene glycol monomethyl ether is probably absorbed by inhalation, dermal and oral routes, but it is unlikely to accumulate.


SECTION 4. FIRST AID MEASURES

Inhalation:
If symptoms are experienced, remove source of contamination or move victim to fresh air. Obtain medical advice immediately.

Skin Contact:
As quickly as possible, flush with lukewarm, gently flowing water for at least 5 minutes or until the chemical is removed. Under running water, remove contaminated clothing, shoes and leather goods (e.g. watchbands, belts). If irritation persists, repeat flushing. Obtain medical advice immediately. Completely decontaminate clothing, shoes and leather goods before re-use or discard.

Eye Contact:
If irritation occurs, immediately flush the contaminated eye(s) with lukewarm, gently flowing water for at least 5 minutes, or until the chemical is removed, while holding the eyelid(s) open. If irritation persists, obtain medical advice immediately.

Ingestion:
Never give anything by mouth if victim is rapidly losing consciousness, is unconscious or convulsing. DO NOT INDUCE VOMITING. Have victim drink 240 to 300 mL (8 to 10 oz.) of water. If vomiting occurs naturally, rinse mouth and repeat administration of water. Obtain medical advice immediately.

First Aid Comments:
Consult a doctor and/or the nearest Poison Control Centre for all exposures except minor instances of inhalation or skin contact.

All first aid procedures should be periodically reviewed by a doctor familiar with the material and its conditions of use in the workplace.



SECTION 5. FIRE FIGHTING MEASURES

Flash Point:
172 deg C (342 deg F) (Setaflash closed cup).(3)

Lower Flammable (Explosive) Limit (LFL/LEL):
Not available

Upper Flammable (Explosive) Limit (UFL/UEL):
Not available

Autoignition (Ignition) Temperature:
Not available

Sensitivity to Mechanical Impact:
Not sensitive. Stable material.

Sensitivity to Static Charge:
Not sensitive. Not combustible.

Fire Hazard Summary:
This material can probably burn if strongly heated.

Extinguishing Media:
No specific data available. Probably can use carbon dioxide, dry chemical, alcohol foam, polymer foam. Water spray may cause frothing.

Fire Fighting Instructions:
Water spray or fog or alcohol foam can be used to extinguish fires involving polypropylene glycol monomethyl ether. Water or foam may cause frothing. However, a water spray or fog that is gently applied to the surface of the liquid, preferably with a fine spray or fog nozzle, will cause frothing that will blanket and extinguish the fire.
Water spray or mist can be used to absorb heat, keep containers cool and protect exposed material. If a leak or spill has not ignited, use water spray to disperse the vapours (dilute the spill to a nonflammable mixture) and protect personnel attempting to stop a leak. Water spray may be used to flush spills away from ignition sources.
Polypropylene glycol monomethyl ether is practically nonhazardous to health. Firefighters may enter the area if positive pressure self-contained breathing apparatus (MSHA/NIOSH approved or equivalent) and full Bunker Gear is worn.



NATIONAL FIRE PROTECTION ASSOCIATION (NFPA) HAZARD IDENTIFICATION

NFPA - Comments:
NFPA has no listing for this chemical in Codes 49 or 325.


SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES

Molecular Weight: Not available. Variable. Polymer.

Conversion Factor:
Not applicable

Physical State: Liquid
Melting Point: Not available
Boiling Point: 310 deg C (590 deg F) (3)
Relative Density (Specific Gravity): 0.985 at 25 deg C C (water = 1) (3)
Solubility in Water: Soluble in all proportions (1,4)
Solubility in Other Liquids: Soluble in all proportions with many organic solvents
Coefficient of Oil/Water Distribution (Partition Coefficient): Not available
pH Value: Not available
Vapour Density: Not available
Vapour Pressure: Very low. 0.00013 kPa (0.001 mm Hg) at 20 deg C.(4)
Saturation Vapour Concentration: 1.3 ppm (0.00013%) (calculated)
Evaporation Rate: Approximately zero (butyl acetate = 1) (3,4)

SECTION 10. STABILITY AND REACTIVITY

Stability:
Normally stable

Hazardous Polymerization:
Will not occur

Incompatibility - Materials to Avoid:

NOTE: Chemical reactions that could result in a hazardous situation (e.g. generation of flammable or toxic chemicals, fire or detonation) are listed here. Many of these reactions can be done safely if specific control measures (e.g. cooling of the reaction) are in place. Although not intended to be complete, an overview of important reactions involving common chemicals is provided to assist in the development of safe work practices.


No information available

Hazardous Decomposition Products:
None reported

Conditions to Avoid:
Temperatures above 172 deg C

Corrosivity to Metals:
Probably not corrosive

Stability and Reactivity Comments:
Some glycol ethers can form peroxides during prolonged storage in contact with air. Formation of peroxides occurs more readily in sunlight. The rate and extent of peroxide formation for this chemical is unknown, but is expected to be low. This is not expected to pose any hazard.


SECTION 11. TOXICOLOGICAL INFORMATION

LD50 (oral, rat): 49 g/kg (2)
LD50 (dermal, rabbit): greater than 20 g/kg (2)


SECTION 16. OTHER INFORMATION

Selected Bibliography:
(1) Patty's industrial hygiene and toxicology. 3rd rev. ed. Vol. 2C. John Wiley & Sons, 1982. p. 3973-3974
(2) RTECS record for poly(oxy(methyl-1,2-ethanediyl),alpha-methyl-omega-hydroxy-. Last updated 9109
(3) Dowfroth (R) 1012 Flotation Frother (Dow Chemical Canada Inc.) Printout from MSDS Database. Date of MSDS: 90/06/18
(4) Dowfroth (R) 250-C Flotation Frother (Dow Chemical Canada Inc.) Printout from MSDS Database. Date of MSDS: 90/06/18

Information on chemicals reviewed in the CHEMINFO database is drawn from a number of publicly available sources. A list of general references used to compile CHEMINFO records is available in the database Help.


Review/Preparation Date: 1993-03-04

Revision Indicators:
TDG 1994-03-01
Fire fighting instructions 1995-01-01
HANDLING AND STORAGE 1995-01-01
Conditions to avoid 1995-01-01
Sampling 1995-11-01
EU class 1995-11-01
US transport 1995-11-01
Respiratory guidelines 1995-11-01
Resistance of materials 1995-11-01
Bibliography 1995-11-01
WHMIS disclosure list 2003-05-28
Carcinogenicity 2003-05-28
PEL-TWA transitional 2003-10-16



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