2-NITROPROPANE (ICSC)

2-NITROPROPANE	ICSC: 0187

Date of Peer Review: March 1995

Isonitropropane
Dimethylnitromethane
sec-Nitropropane

CAS #

79-46-9

C₃H₇NO₂ / CH₃CHNO₂CH₃

RTECS #

TZ5250000

Molecular mass: 89.1

UN #

2608

EC #

609-002-00-1

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Flammable. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames, NO sparks, and NO smoking.	Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION	Above 24°C explosive vapour/air mixtures may be formed.	Above 24°C use a closed system, ventilation, and explosion-proof electrical equipment.	In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position.

EXPOSURE		AVOID ALL CONTACT! AVOID EXPOSURE OF (PREGNANT) WOMEN!	IN ALL CASES CONSULT A DOCTOR!
Inhalation	Cough. Dizziness. Drowsiness. Headache. Nausea. Vomiting. Weakness.	Ventilation, local exhaust, or breathing protection.	Refer for medical attention.
Skin		Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower.
Eyes	Redness. Pain.	Face shield or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion	(Further see Inhalation).	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Refer for medical attention.

SPILLAGE DISPOSAL

PACKAGING & LABELLING

Evacuate danger area in case of a large spillage! Consult an expert! Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. Personal protection: self-contained breathing apparatus.

EU Classification
Symbol: T
R: 45-10-20/22
S: 53-45
Note: [E]
UN Classification
UN Hazard Class: 3
UN Pack Group: III

EMERGENCY RESPONSE

STORAGE

Transport Emergency Card: TEC (R)-30GF1-III
NFPA Code: H2; F3; R1

Fireproof. Separated from strong bases, strong acids, amines.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities © IPCS, CEC 1999

SEE IMPORTANT INFORMATION ON BACK

2-NITROPROPANE

ICSC: 0187

IMPORTANT DATA

PHYSICAL STATE; APPEARANCE:
COLOURLESS OILY LIQUID.

CHEMICAL DANGERS:
The substance decomposes on burning producing nitrogen oxides. Shock-sensitive compounds are formed with acids, amines, inorganic bases and heavy metal oxides. Reacts with activated carbon causing fire hazard. May be decomposed by the activated carbon in respirator filters.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 10 ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2004).
MAK: Carcinogen category: 2; (DFG 2004).

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The vapour of this substance is irritating to the eyes and the respiratory tract. Exposure far above the OEL could cause liver damage. Exposure at high levels may result in death.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the liver and nervous system, resulting in nausea, vomiting, diarrhea, anorexia and severe headache. This substance is possibly carcinogenic to humans. Animal tests show that this substance possibly causes toxic effects upon human reproduction.

PHYSICAL PROPERTIES

Boiling point: 120°C
Melting point: -93°C
Relative density (water = 1): 0.99
Solubility in water, ml/100 ml at 25°C: 1.7
Vapour pressure, kPa at 20°C: 1.7
Relative vapour density (air = 1): 3.1

Relative density of the vapour/air-mixture at 20°C (air = 1): 1.04
Flash point: 24°C c.c.
Auto-ignition temperature: 428°C
Explosive limits, vol% in air: 2.6-11
Octanol/water partition coefficient as log Pow: 0.93

ENVIRONMENTAL DATA

NOTES

Depending on the degree of exposure, periodic medical examination is indicated. The odour warning when the exposure limit value is exceeded is insufficient. NiPar S-20 and NiPar S-30 are trade names.
Card has been partly updated in April 2005. See sections Occupational Exposure Limits, Emergency Response.

ADDITIONAL INFORMATION

LEGAL NOTICE

Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

See Also:
        2-Nitropropane (CHEMINFO)
        2-Nitropropane (EHC 138, 1992)