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p-NITROPHENOL ICSC: 0066
Date of Peer Review: November 1998

4-Nitrophenol
4-Hydroxynitrobenzene
CAS # 100-02-7 C6H5NO3
RTECS # SM2275000 Molecular mass: 139.1
UN # 1663
EC # 609-015-00-2
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, water spray, foam, carbon dioxide.
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
PREVENT DISPERSION OF DUST! STRICT HYGIENE!

Inhalation Blue lips or finger nails. Blue skin. Cough. Burning sensation. Confusion. Convulsions. Dizziness. Headache. Nausea. Sore throat. Unconsciousness. Weakness.
Local exhaust or breathing protection.
Fresh air, rest. Refer for medical attention.
Skin MAY BE ABSORBED! Redness. (Further see Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes Redness. Pain.
Safety spectacles, face shield or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Abdominal pain. Sore throat. Vomiting. (See Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Rest. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment. Personal protection: P2 filter respirator for harmful particles.
Do not transport with food and feedstuffs.
EU Classification
Symbol: Xn
R: 20/21/22-33
S: (2-)-28
UN Classification
UN Hazard Class: 6.1
UN Pack Group: III
EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61S1663
NFPA Code: H3; F1; R2;
Separated from combustible and reducing substances, food and feedstuffs. Well closed.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2004

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p-NITROPHENOL ICSC: 0066
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS TO PALE YELLOW CRYSTALS

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air.

CHEMICAL DANGERS:
May explode on heating. The substance decomposes on heating producing toxic fumes including nitrogen oxides. Mixtures with potassium hydroxide are explosive.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

INHALATION RISK:
Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes, the skin and the respiratory tract. Yellow staining of the skin. The substance may cause effects on the blood, resulting in formation of methaemoglobin. The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact may cause skin sensitization.
PHYSICAL PROPERTIES
Boiling point (decomposes): 279C
Melting point: 111-116C
Density: 1.5 g/cm
Solubility in water, g/100 ml at 20C: 1.24
Vapour pressure, Pa at 20C: 0.0032
Flash point: 169C
Auto-ignition temperature: 490C
Octanol/water partition coefficient as log Pow: 1.91
ENVIRONMENTAL DATA
The substance is toxic to aquatic organisms.
NOTES
Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Card has been partly updated in April 2005. See section Physical properties.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2004