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NITROBENZENE ICSC: 0065
Date of Peer Review: September 1993

Nitrobenzol
CAS # 98-95-3 C6H5NO2
RTECS # DA6475000 Molecular mass: 123.1
UN # 1662
EC # 609-003-00-7
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION Above 88C explosive vapour/air mixtures may be formed. Risk of fire and explosion (see Chemical Dangers).
Above 88C use a closed system, ventilation.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
PREVENT GENERATION OF MISTS! STRICT HYGIENE!
IN ALL CASES CONSULT A DOCTOR!
Inhalation Headache. Blue lips or finger nails. Blue skin. Dizziness. Nausea. Weakness. Unconsciousness.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Refer for medical attention.
Skin MAY BE ABSORBED! (Further see Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes
Safety goggles.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion
Do not eat, drink, or smoke during work.
Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT absorb in saw-dust or other combustible absorbents. Personal protection: complete protective clothing including self-contained breathing apparatus.
Do not transport with food and feedstuffs.
EU Classification
Symbol: T, N
R: 23/24/25-40-48/23/24-51/53-62
S: (1/2-)-28-36/37-45-61
UN Classification
UN Hazard Class: 6.1
UN Pack Group: II
EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61S1662
NFPA Code: H 3; F 2; R 0;
Separated from combustible and reducing substances, strong oxidants, strong acids, food and feedstuffs.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2004

SEE IMPORTANT INFORMATION ON BACK


NITROBENZENE ICSC: 0065
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
PALE YELLOW OILY LIQUID, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS:
On combustion, forms toxic and corrosive fumes including nitrogen oxides. Reacts violently with strong oxidants reducing agents causing fire and explosion hazard. Attacks many plastics. Forms explosive (thermally unstable) substances or mixtures with many organic and inorganic compounds like oxidants, aluminium chloride with phenol, potassium hydroxide anhydrous or with small amounts of methanol, aniline with glycerol, phosphoruspentachloride, nitric acid, sulphuric acid, potassium.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 1 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued; (ACGIH 2004).
MAK: skin absorption (H); Carcinogen category: 3B; (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and through the skin.

INHALATION RISK:
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20C; on spraying or dispersing, however, much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the blood cells, resulting in formation of methaemoglobin. Exposure could cause lowering of consciousness. The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the blood forming organs. It may have effects on the liver.
PHYSICAL PROPERTIES
Boiling point: 211C
Melting point: 6C
Relative density (water = 1): 1.2
Solubility in water, g/100 ml: 0.2
Vapour pressure, Pa at 20C: 20
Relative vapour density (air = 1): 4.2
Relative density of the vapour/air-mixture at 20C (air = 1): 1.00
Flash point: 88C c.c.
Auto-ignition temperature: 480C
Explosive limits, vol% in air: 1.8-40
Octanol/water partition coefficient as log Pow: 1.86
ENVIRONMENTAL DATA

NOTES
Use of alcoholic beverages enhances the harmful effect. Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Do NOT take working clothes home. On distillation, do NOT evaporate to dryness because of the explosion hazard.
Card has been partly updated in April 2005. See sections Occupational Exposure Limits, EU classification.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2004
See Also:
        Nitrobenzene (EHC)
        Nitrobenzene (IARC Summary & Evaluation, Volume 65)