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METHYL ISOBUTYL KETONE ICSC: 0511
Date of peer-review: October 1997

4-Methyl-2-pentanone
Isopropylacetone
Hexone
CAS # 108-10-1 C6H12O / CH3COCH2CH(CH3)2
RTECS # SA9275000 Molecular mass: 100.2
UN # 1245
EC # 606-004-00-4
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Highly flammable.
NO open flames, NO sparks, and NO smoking.
Powder, AFFF, foam, carbon dioxide.
EXPLOSION Vapour/air mixtures are explosive.
Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
PREVENT GENERATION OF MISTS!

Inhalation Cough. Diarrhoea. Dizziness. Headache. Nausea. Sore throat. Unconsciousness. Vomiting. Weakness. Loss of appetite.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Refer for medical attention.
Skin Dry skin. Redness. Pain.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes Redness. Pain.
Safety spectacles.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Abdominal pain. (Further see Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place (extra personal protection: filter respirator for organic gases and vapours).
Airtight.
EU Classification
Symbol: F
R: 11
S: (2-)9-16-23-33
UN Classification
UN Hazard Class: 3
UN Pack Group: II
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-610 NFPA Code: H2; F3; R0;
Fireproof. Separated from strong oxidants. Well closed.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2001

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METHYL ISOBUTYL KETONE ICSC: 0511
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
The vapour mixes well with air, explosive mixtures are easily formed.

CHEMICAL DANGERS:
The substance can form explosive peroxides upon exposure to air. Reacts violently with strong oxidants and reducing agents.

OCCUPATIONAL EXPOSURE LIMITS:
TLV (as TWA): 50 ppm; 205 mg/m^3; (as STEL): 75 ppm; 307 mg/m^3 (ACGIH 1997).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance and the vapour irritates the eyes, the skin and the respiratory tract. Swallowing the liquid may cause aspiration into the lungs with the risk of chemical pneumonitis. The substance may cause effects on the central nervous system at high concentrations , resulting in narcosis.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact with skin may cause dermatitis.
PHYSICAL PROPERTIES
Boiling point: 117-118C
Melting point: -84.7C
Relative density (water = 1): 0.80
Solubility in water, g/100 ml at 20C: 1.91
Vapour pressure, kPa at 20C: 2.1
Relative vapour density (air = 1): 3.45
Flash point: 14C c.c.
Auto-ignition temperature: 460C
Explosive limits, vol% in air: 1.4-7.5
Octanol/water partition coefficient as log Pow: 1.38
ENVIRONMENTAL DATA

NOTES
MIBK is commonly used name. Check for peroxides prior to distillation; eliminate if found.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2001

See Also:
        Methyl isobutyl ketone (CHEMINFO)
        Methyl isobutyl ketone (EHC 117, 1990)