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METHOMYL ICSC: 0177
Date of Peer Review: October 2005

S-Methyl-N-(methylcarbamoyloxy)thioacetimidate
Ethanimidothioic acid, N-{{(methylamino)carbonyl}oxy}-, methyl ester
Methyl N-{(methylamino)carbonyloxy}ethanimidothioate
CAS # 16752-77-5 C5H10N2O2S
RTECS # AK2975000 Molecular mass: 162.2
UN # 2757
EC Index # 006-045-00-2
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible under specific conditions. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Water spray, foam, powder, carbon dioxide.
EXPLOSION


EXPOSURE
PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!

Inhalation Pupillary constriction, muscle cramp, excessive salivation. Muscle twitching. Dizziness. Headache. Sweating. Laboured breathing. Unconsciousness.
Local exhaust or breathing protection.
Fresh air, rest. Half-upright position. Refer for medical attention. See Notes.
Skin
Protective gloves.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
Eyes Redness. Blurred vision.
Safety goggles or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Abdominal cramps. Convulsions. Diarrhoea. Nausea. Vomiting. Weakness. (Further see Inhalation).
Do not eat, drink, or smoke during work. Wash hands before eating.
Induce vomiting (ONLY IN CONSCIOUS PERSONS!). See Notes. Give a slurry of activated charcoal in water to drink. Refer for medical attention immediately.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Personal protection: P3 filter respirator for toxic particles. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place.
Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. Marine pollutant.
EU Classification
Symbol: T+, N
R: 28-50/53
S: (1/2-)-22-36/37-45-60-61
UN Classification
UN Hazard Class: 6.1
UN Pack Group: II
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-61GT7-II
Store in an area without drain or sewer access. Dry. Keep in a well-ventilated room. Separated from strong bases, food and feedstuffs.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
METHOMYL ICSC: 0177
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
WHITE CRYSTALS, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS:
The substance decomposes on heating and on burning producing toxic and corrosive fumes including nitrogen oxides, sulfur oxides, hydrogen cyanide, methylisocyanate. Reacts with strong bases.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 2.5 mg/m as TWA; A4 (not classifiable as a human carcinogen); BEI issued; (ACGIH 2005).
MAK not established.
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

INHALATION RISK:
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20C; on spraying or dispersing, however, much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes. The substance may cause effects on the nervous system, resulting in convulsions and respiratory depression. Cholinesterase inhibitor. Exposure far above the OEL may result in death.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the blood, resulting in anaemia.
PHYSICAL PROPERTIES
Melting point: 78C
Density: 1.3 g/cm
Solubility in water, g/100 ml at 25C: 5.8 (moderate)
Vapour pressure, Pa at 25C: negligible
Octanol/water partition coefficient as log Pow: 1.24
ENVIRONMENTAL DATA
The substance is very toxic to aquatic organisms. This substance may be hazardous in the environment; special attention should be given to birds and honey bees. This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal.
NOTES
Methomyl is a mixture of (Z)- and (E)-isomers. If the pesticide is present in a formulation containing hydrocarbon solvents, vomiting should not be induced. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvents also consult the ICSCs of these materials. Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Depending on the degree of exposure, periodic medical examination is suggested. Du Pont 1179, Flytek, Lannate, Lanox, Methavin, Methomex, Nudrin are trade names.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005
See Also:
        Methomyl (EHC 178, 1996)
        Methomyl (PDS)