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METHYLACETOACETATE ICSC: 1086
Date of Peer Review: November 2003

Acetoacetic acid methyl ester
Butanoic acid, 3-oxo-, methyl ester
1-Methoxybutane-1,3-dione
CAS # 105-45-3 C5H8O3
RTECS # AK5775000 Molecular mass: 116.1
UN #
EC # 607-137-00-0
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible.
NO open flames.
Alcohol-resistant foam, powder, carbon dioxide.
EXPLOSION Above 77C explosive vapour/air mixtures may be formed.
Above 77C use a closed system, ventilation.

EXPOSURE


Inhalation Cough. Dizziness. Drowsiness. Headache. Sore throat.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Refer for medical attention.
Skin
Protective gloves.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
Eyes Redness. Pain.
Safety goggles.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water. (Extra personal protection: filter respirator for organic gases and vapours.)
EU Classification
Symbol: Xi
R: 36
S: (2-)-26
UN Classification

EMERGENCY RESPONSE STORAGE
NFPA Code: H2; F2; R0;
Separated from oxidants.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 1999

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METHYLACETOACETATE ICSC: 1086
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

CHEMICAL DANGERS:
The substance decomposes on burning producing irritating fumes. Reacts with oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established. MAK not established.
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour.

INHALATION RISK:
No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes and the respiratory tract. Exposure may result in lowering of consciousness.

PHYSICAL PROPERTIES
Boiling point: 171.7C
Melting point: -27C
Relative density (water = 1): 1.08
Solubility in water, g/100 ml: 50
Vapour pressure, kPa at 20C: 0.17
Relative vapour density (air = 1): 4.0
Relative density of the vapour/air-mixture at 20C (air = 1): 1.01
Flash point: 77C c.c.
Auto-ignition temperature: 280C
Explosive limits, vol% in air: 1.4-14.5
Octanol/water partition coefficient as log Pow: -0.26
ENVIRONMENTAL DATA

NOTES

ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 1999