INTOX Home Page
MALEIC ANHYDRIDE ICSC: 0799
Date of Peer Review: October 2005

2,5-Furandione
Dihydro-2,5-dioxofuran
Maleic acid anhydride
cis-Butenedioic anhydride
CAS # 108-31-6 C4H2O3
RTECS # ON3675000 Molecular mass: 98.1
UN # 2215
EC Index # 607-096-00-9
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible.
NO open flames.
Water spray. Alcohol-resistant foam. Carbon dioxide. NO powder.
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE
STRICT HYGIENE! PREVENT DISPERSION OF DUST!

Inhalation Burning sensation. Cough. Sore throat. Shortness of breath. Wheezing.
Local exhaust or breathing protection.
Fresh air, rest. Half-upright position. Refer for medical attention.
Skin Dry skin. Redness. Pain. (See Notes).
Protective gloves. OR Heat-insulating gloves. See Notes. Protective clothing.
First rinse with plenty of water, then remove contaminated clothes and rinse again.
Eyes Redness. Pain. Burns.
Safety goggles or eye protection in combination with breathing protection if powder.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Nausea. Abdominal pain. Burning sensation. Vomiting. Diarrhoea.
Do not eat, drink, or smoke during work.
Rinse mouth. Give plenty of water to drink. Do NOT induce vomiting. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Personal protection: P3 filter respirator for toxic particles. Chemical protection suit. Use face shield. Thermal gloves. See Notes. Sweep spilled substance into covered containers.
Airtight. Do not transport with food and feedstuffs.
EU Classification
Symbol: C
R: 22-34-42/43
S: (2-)-22-26-36/37/39-45
UN Classification
UN Hazard Class: 8
UN Pack Group: III
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-80S2215-S
NFPA Code: H3; F1; R1;
Dry. Separated from strong oxidants, strong bases, food and feedstuffs.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
MALEIC ANHYDRIDE ICSC: 0799
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS OR WHITE CRYSTALS, WITH PUNGENT ODOUR.

CHEMICAL DANGERS:
The solution in water is a medium strong acid. Reacts with strong bases and strong oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.1 ppm as TWA; A4 (not classifiable as a human carcinogen); SEN; (ACGIH 2005).
MAK: 0.1 ppm, 0.41 mg/m; sensitization of respiratory tract and skin (Sah); Peak limitation category: I(1); Pregnancy risk group: C; (DFG 2005).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is severely irritating to the eyes, the skin and the respiratory tract. Inhalation of the substance may cause asthma-like reactions.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation exposure may cause asthma.
PHYSICAL PROPERTIES
Boiling point: 202C
Melting point: 53C
Density: 1.5 g/cm
Solubility in water: reaction
Vapour pressure, Pa at 25C: 25
Relative vapour density (air = 1): 3.4
Flash point: 102C c.c.
Auto-ignition temperature: 477C
Explosive limits, vol% in air: 1.4-7.1
ENVIRONMENTAL DATA

NOTES
Reacts violently with fire extinguishing agents such as powder. Depending on the degree of exposure, periodic medical examination is suggested. The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Anyone who has shown symptoms of asthma due to this substance should avoid all further contact with this substance. Maleic anhydride is transported also as hot liquid (70C); contact of the skin should be avoided. The odour warning when the exposure limit value is exceeded is insufficient.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005
See Also:
        Maleic anhydride molten liquid (CHEMINFO)
        Maleic anhydride solid (CHEMINFO)