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ISOBUTYLAMINE ICSC: 1253
Date of Peer Review: April 2005

2-Methylpropylamine
2-Methyl-1-propanamine
1-Amino-2-methylpropane
CAS # 78-81-9 C4H11N / (CH3)2CHCH2NH2
RTECS # NP9900000 Molecular mass: 73.1
UN # 1214
EC #
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames, NO sparks, and NO smoking.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION Vapour/air mixtures are explosive.
Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
Inhalation Burning sensation. Cough. Shortness of breath. Laboured breathing. Symptoms may be delayed (see Notes).
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Skin Pain. Redness. Skin burns.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes Redness. Pain. Severe deep burns.
Face shield or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Abdominal pain. Burning sensation. Shock or collapse.
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking liquid in sealable containers. Cautiously neutralize spilled liquid. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Then wash away with plenty of water.
Unbreakable packaging; put breakable packaging into closed unbreakable container.
EU Classification
UN Classification
UN Hazard Class: 3
UN Subsidiary Risks: 8
UN Pack Group: II
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-30GFC-II
NFPA Code: H3; F3; R0
Fireproof. Separated from strong oxidants, strong acids, food and feedstuffs.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 1999

SEE IMPORTANT INFORMATION ON BACK
ISOBUTYLAMINE ICSC: 1253
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
The vapour is heavier than air and may travel along the ground; distant ignition possible.

CHEMICAL DANGERS:
The substance decomposes on burning producing toxic gases including nitrogen oxides. The solution in water is a medium strong base. Reacts violently with acids and oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: 5 ppm, 15 mg/m; skin absorption (H); Peak limitation category: I(2); Pregnancy risk group: IIc; (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is corrosive to the eyes, the skin and the respiratory tract. Corrosive on ingestion. Inhalation of the substance may cause lung oedema (see Notes). The effects may be delayed. Medical observation is indicated.

PHYSICAL PROPERTIES
Boiling point: 68-69C
Melting point: -85C
Relative density (water = 1): 0.72
Solubility in water: miscible
Vapour pressure, kPa at 18.8C: 13.3
Relative vapour density (air = 1): 2.5
Relative density of the vapour/air-mixture at 20C (air = 1): 1.2
Flash point: -9.0C c.c.
Auto-ignition temperature: 378C
Explosive limits, vol% in air: 3.4-9
Octanol/water partition coefficient as log Pow: 0.73
ENVIRONMENTAL DATA

NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 1999
See Also:
        Isobutanolamine (ICSC)