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CYCLOHEXYL ISOCYANATE ICSC: 0856
Date of peer-review: October 1997

Isocyanatocyclohexane
Isocyanic acid cyclohexyl ester
CHI
CAS # 3173-53-3 C7H11NO / C6H11-N=C=O
RTECS # NQ8650000 Molecular mass: 125.17
UN # 2488
EC #
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames, NO sparks, and NO smoking.
Foam, alcohol-resistant foam, powder, carbon dioxide, dry sand.
EXPLOSION Above 48C explosive vapour/air mixtures may be formed.
Above 48C use a closed system, ventilation, and explosion-proof electrical equipment. Prevent build-up of electrostatic charges (e.g., by grounding).
In case of fire: cool drums, etc., by spraying with water but avoid contact of the substance with water. Combat fire from a sheltered position.
EXPOSURE
AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
Inhalation Burning sensation. Cough. Headache. Laboured breathing. Shortness of breath. Sore throat. Symptoms may be delayed (see Notes). (see Ingestion).
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.
Skin Redness.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention. Wear protective gloves when administering first aid.
Eyes Watering of eyes. Redness. Pain. Blurred vision. Severe deep burns.
Face shield, or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion
Do not eat, drink, or smoke during work.
Give a slurry of activated charcoal in water to drink. Do NOT induce vomiting. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Consult an expert! Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer (extra personal protection: complete protective clothing including self-contained breathing apparatus).
Do not transport with food and feedstuffs.
EU Classification
UN Classification
UN Hazard Class: 6.1
UN Subsidiary Risks: 3
UN Pack Group: I
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-625
Fireproof. Separated from strong oxidants, strong bases, strong acids, food and feedstuffs. Dry. Keep in a well-ventilated room.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2001

SEE IMPORTANT INFORMATION ON BACK


CYCLOHEXYL ISOCYANATE ICSC: 0856
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID , WITH PUNGENT ODOUR.

PHYSICAL DANGERS:
The vapour is heavier than air and may travel along the ground; distant ignition possible.

CHEMICAL DANGERS:
The substance may polymerize due to heating and under the influence of various chemicals including organometallic compounds. The substance decomposes on burning producing toxic fumes (hydrogen cyanide nitrogen oxides). Reacts with oxidants and strong bases, water, alcohol, acids and amines.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK:
No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
Tear drawing. The substance irritates the eyes, the skin and the respiratory tract. See Notes.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation exposure may cause asthma (see Notes).
PHYSICAL PROPERTIES
Boiling point: 168C
Relative density (water = 1): 0.98
Solubility in water: reaction
Relative vapour density (air = 1): 4.3
Flash point: 48C c.c.
ENVIRONMENTAL DATA

NOTES
Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Anyone who has shown symptoms of asthma due to this substance should avoid all further contact with this substance. Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2001

See Also:
        Cyclohexyl isocyanate (CHEMINFO)