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CHLOROFORM ICSC: 0027
Date of Peer Review: April 2000

Trichloromethane
Methane trichloride
Formyl trichloride
CAS # 67-66-3 CHCl3
RTECS # FS9100000 Molecular mass: 119.4
UN # 1888
EC # 602-006-00-4
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Not combustible. See Notes. Gives off irritating or toxic fumes (or gases) in a fire.

In case of fire in the surroundings: use appropriate extinguishing media.
EXPLOSION

In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!

Inhalation Cough. Dizziness. Drowsiness. Headache. Nausea. Unconsciousness.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin Redness. Pain. Dry skin.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes Redness. Pain.
Face shield or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Abdominal pain. Vomiting. (Further see Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Give plenty of water to drink. Rest. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment. Personal protection: complete protective clothing including self-contained breathing apparatus.
Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs.
EU Classification
Symbol: Xn
R: 22-38-40-48/20/22
S: (2-)-36/37
UN Classification
UN Hazard Class: 6.1
UN Pack Group: III
EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61S1888
NFPA Code: H 2; F 0; R 0;
Separated from food and feedstuffs and incompatible materials, (see Chemical Dangers). Ventilation along the floor.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2004

SEE IMPORTANT INFORMATION ON BACK


CHLOROFORM ICSC: 0027
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
VOLATILE COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
The vapour is heavier than air.

CHEMICAL DANGERS:
On contact with hot surfaces or flames this substance decomposes forming toxic and corrosive fumes (hydrogen chloride ICSC0163, phosgene ICSC0007 and chlorine fumes ICSC0126). Reacts violently with strong bases, strong oxidants, some metals, such as aluminium, magnesium and zinc, causing fire and explosion hazard. Attacks plastic, rubber and coatings.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 10 ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2004).
MAK: 0.5 ppm, 2.5 mg/m; Peak limitation category: II(2); skin absorption (H); Carcinogen category: 4; Pregnancy risk group: C; (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes. The substance may cause effects on the central nervous system, liver and kidneys. The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The liquid defats the skin. The substance may have effects on the liver and kidneys. This substance is possibly carcinogenic to humans.
PHYSICAL PROPERTIES
Boiling point: 62C
Melting point: -64C
Relative density (water = 1): 1.48
Solubility in water, g/100 ml at 20C: 0.8
Vapour pressure, kPa at 20C: 21.2
Relative vapour density (air = 1): 4.12
Relative density of the vapour/air-mixture at 20C (air = 1): 1.7
Octanol/water partition coefficient as log Pow: 1.97
ENVIRONMENTAL DATA
The substance is toxic to aquatic organisms.
NOTES
Turns combustible on addition of small amounts of a flammable substance or an increase in the oxygen content of the air. Use of alcoholic beverages enhances the harmful effect. Depending on the degree of exposure, periodic medical examination is indicated. The odour warning when the exposure limit value is exceeded is insufficient. Do NOT use in the vicinity of a fire or a hot surface, or during welding.
Card has been partly updated in April 2005. See section Occupational Exposure Limits.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2004
See Also:
        Chloroform (CHEMINFO)
        Chloroform (EHC 163, 1994)
        Chloroform (IARC Summary & Evaluation, Supplement 7, 1987)
        Chloroform (IARC Summary & Evaluation, Volume 1, 1972)
        Chloroform (IARC Summary & Evaluation, Volume 20, 1979)
        Chloroform (PIM 121)