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AMITROLE ICSC: 0631
Date of Peer Review: April 1994

1,2,4-Triazol-3-ylamine
3-Amino-1H-1,2,4-triazole
Aminotriazole
CAS # 61-82-5 C2H4N4
RTECS # XZ3850000 Molecular mass: 84.1
UN # 2588
EC Index # 613-011-00-6
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

In case of fire in the surroundings: use appropriate extinguishing media.
EXPLOSION


EXPOSURE
STRICT HYGIENE!

Inhalation
Ventilation (not if powder), local exhaust, or breathing protection.
Refer for medical attention.
Skin
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
Eyes
Face shield or eye protection in combination with breathing protection if powder.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Do NOT wash away into sewer. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Personal protection: P3 filter respirator for toxic particles.
Do not transport with food and feedstuffs. Severe marine pollutant.
EU Classification
Symbol: Xn, N
R: 48/22-63-51/53
S: (2-)-13-36/37-61
UN Classification
UN Hazard Class: 6.1
UN Pack Group: III
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-61GT7-III
Separated from food and feedstuffs, incompatible materials. See Chemical Dangers. Keep in the dark. Keep in a well-ventilated room.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
AMITROLE ICSC: 0631
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
ODOURLESS, COLOURLESS CRYSTALS.

CHEMICAL DANGERS:
The substance decomposes on heating producing toxic fumes 0f nitrogen oxides. The substance is a weak base. Reacts with strong acids, strong oxidants, acid chlorides and acid anhydrides. Attacks iron, copper and aluminium.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.2 mg/m as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2004).
MAK: (Inhalable fraction) 0.2 mg/m; Peak limitation category: II(8); Carcinogen category: 3B; Pregnancy risk group: C; (DFG 2005).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

INHALATION RISK:
Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the thyroid.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the thyroid, resulting in goitrogenic effects.
PHYSICAL PROPERTIES
Melting point: 159C
Solubility in water: good
Octanol/water partition coefficient as log Pow: -0.65
ENVIRONMENTAL DATA
This substance may be hazardous in the environment; special attention should be given to plants.
NOTES
Temperature of decomposition unknown in literature. Depending on the degree of exposure, periodic medical examination is suggested. Card has been partly updated in October 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005
See Also:
        Amitrole (EHC 158, 1994)
        Amitrole (IARC Summary & Evaluation, Supplement 7, 1987)
        Amitrole (IARC Summary & Evaluation, Volume 41, 1986)
        Amitrole (IARC Summary & Evaluation, Volume 7, 1974)
        Amitrole (PDS)
        Amitrole (PIM 648)