For definition of Groups, see Preamble Evaluation.
VOL.: 53 (1991) (p. 93)
CAS No.: 116-06-3
Chem. Abstr. Name: 2-Methyl-2-(methylthio)propanal, O-[(methylamino)carbonyl]oxime
Aldicarb is a moderately persistent systemic insecticide, acaricide and nematicide formulated as granules. It was first used in 1970 and is applied mainly on cotton and potatoes.
Exposure to aldicarb may occur during its production and application and, at lower levels, via contamination of groundwater and consumption of food containing residues.
No data were available to the Working Group.
Aldicarb has not been tested adequately for carcinogenicity in experimental animals.
Aldicarb is highly acutely toxic: it is one of the most potent cholinesterase-inhibiting carbamate insecticides.
No data were available on the genetic and related effects of aldicarb in humans.
Aldicarb induced chromosomal aberrations in rat bone-marrow cells in vivo. It induced various kinds of chromosomal damage and gene mutation in cultured human cells and induced gene mutation in rodent cells. It did not cause mutation in bacteria.
No data were available from studies in humans.
There is inadequate evidence for the carcinogenicity of aldicarb in experimental animals.
Aldicarb is not classifiable as to its carcinogenicity to humans (Group 3).
For definition of the italicized terms, see Preamble Evaluation.
Last updated: 20 November 1997
See Also: Aldicarb (EHC 121, 1991) Aldicarb (ICSC) Aldicarb (PDS)