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ACRYLAMIDE ICSC: 0091
Date of Peer Review: April 2000

2-Propene amide
Acrylic acid amide
Vinyl amide
CAS # 79-06-1 C3H5NO / CH2=CHCONH2
RTECS # AS3325000 Molecular mass: 71.1
UN # 2074
EC Index # 616-003-00-0
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE
PREVENT DISPERSION OF DUST! AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
Inhalation Cough. Sore throat. Weakness.
Local exhaust or breathing protection.
Fresh air, rest. Refer for medical attention.
Skin MAY BE ABSORBED! Redness. Pain. (Further see Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes Redness. Pain.
Face shield or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Abdominal pain. Weakness.
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give plenty of water to drink. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Consult an expert! Sweep spilled substance into containers. Carefully collect remainder, then remove to safe place. Chemical protection suit including self-contained breathing apparatus.
Special material.
EU Classification
Symbol: T
R: 45-46-20/21-25-36/38-43-48/23/24/25-62
S: 53-45
Note: [D, E]
UN Classification
UN Hazard Class: 6.1
UN Pack Group: III
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-61GT2-III
NFPA Code: H3; F2; R2;
Separated from oxidants. Cool. Keep in the dark. Well closed.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
ACRYLAMIDE ICSC: 0091
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
WHITE CRYSTALS.

CHEMICAL DANGERS:
The substance will polymerize violently due to heating above 85C or under the influence of light and oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.03 mg/m as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2004).
MAK: H; Carcinogen category: 2; Germ cell mutagen group: 2; (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

INHALATION RISK:
Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes, the skin and the respiratory tract. The substance may cause effects on the central nervous system.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the nervous system, resulting in peripheral nerve damage. This substance is probably carcinogenic to humans. May cause heritable genetic damage in humans.
PHYSICAL PROPERTIES
Melting point: 84.5C
Density: 1.13 g/cm
Solubility in water, g/100 ml at 25C: 204
Vapour pressure, Pa at 20C: 1
Relative vapour density (air = 1): 2.45
Flash point: 138C c.c.
Auto-ignition temperature: 424C
Octanol/water partition coefficient as log Pow: -1.65 - -0.67
ENVIRONMENTAL DATA
This substance may be hazardous to the environment; special attention should be given to fish.
NOTES
Depending on the degree of exposure, periodic medical examination is suggested. Do NOT take working clothes home.
Card has been partly updated in October 2004. See sections Occupational Exposure Limits, EU classification, Emergency Response.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005
See Also:
        Acrylamide (EHC 49, 1985)
        Acrylamide (IARC Summary & Evaluation, Volume 60, 1994)
        Acrylamide (PIM 652)
        Acrylamide solid (CHEMINFO)
        Acrylamide solutions (CHEMINFO)