INTOX Home Page
ACETONE ICSC: 0087
Date of Peer Review: April 1994

2-Propanone
Dimethyl ketone
Methyl ketone
CAS # 67-64-1 C3H6O / CH3-CO-CH3
RTECS # AL3150000 Molecular mass: 58.1
UN # 1090
EC Index # 606-001-00-8
TYPES OF HAZARD / EXPOSURE ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE FIGHTING
FIRE Highly flammable.
NO open flames, NO sparks, and NO smoking.
Powder, alcohol-resistant foam, water in large amounts, carbon dioxide.
EXPLOSION Vapour/air mixtures are explosive.
Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE


Inhalation Sore throat. Cough. Confusion. Headache. Dizziness. Drowsiness. Unconsciousness.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Refer for medical attention.
Skin Dry skin.
Protective gloves.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
Eyes Redness. Pain. Blurred vision. Possible corneal damage.
Safety spectacles or face shield. Contact lenses should not be worn.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion Nausea. Vomiting. (Further see Inhalation). (Further see Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. Then wash away with plenty of water. Personal protection: self-contained breathing apparatus.
EU Classification
Symbol: F, Xi
R: 11-36-66-67
S: (2-)-9-16-26
UN Classification
UN Hazard Class: 3
UN Pack Group: II
EMERGENCY RESPONSE STORAGE
Transport Emergency Card: TEC (R)-30S1090
NFPA Code: H 1; F 3; R 0;
Fireproof. Separated from strong oxidants.
IPCS
International
Programme on
Chemical Safety
Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities IPCS, CEC 2005

SEE IMPORTANT INFORMATION ON BACK
ACETONE ICSC: 0087
IMPORTANT DATA
PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID, WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
The vapour is heavier than air and may travel along the ground; distant ignition possible.

CHEMICAL DANGERS:
The substance can form explosive peroxides on contact with strong oxidants such as acetic acid, nitric acid, hydrogen peroxide. Reacts with chloroform and bromoform under basic conditions, causing fire and explosion hazard. Attacks plastic.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 500 ppm as TWA, 750 ppm as STEL; A4 (not classifiable as a human carcinogen); BEI issued; (ACGIH 2004).
MAK: 500 ppm 1200 mg/m Peak limitation category: I(2); Pregnancy risk group: IIc; (DFG 2004).
ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and through the skin.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20C ; on spraying or dispersing, however, much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
The vapour irritates the eyes and the respiratory tract. The substance may cause effects on the central nervous system, liver, kidneys and gastrointestinal tract.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the blood and bone marrow.
PHYSICAL PROPERTIES
Boiling point: 56C
Melting point: -95C
Relative density (water = 1): 0.8
Solubility in water: miscible
Vapour pressure, kPa at 20C: 24
Relative vapour density (air = 1): 2.0
Relative density of the vapour/air-mixture at 20C (air = 1): 1.2
Flash point: -18C c.c.
Auto-ignition temperature: 465C
Explosive limits, vol% in air: 2.2-13
Octanol/water partition coefficient as log Pow: -0.24
ENVIRONMENTAL DATA

NOTES
Use of alcoholic beverages enhances the harmful effect. Card has been partly updated in October 2005. See sections Occupational Exposure Limits, EU classification.
ADDITIONAL INFORMATION


LEGAL NOTICE Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information
IPCS, CEC 2005
See Also:
        Acetone (CHEMINFO)
        Acetone (EHC 207, 1998)